1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (also known as DOTA) is an organic compound with the formula (CH2CH2NCH2CO2H)4. The molecule consists of a central 12-membered tetraaza (i.e., containing four nitrogen atoms) ring.
B. 1,4,7,10-Tetraazacyclododecane (2). A 1-L, three-necked, round-bottomed flask charged with 8.96 g (54.6 mmol) of 2,3,5,6,8,9-hexahydrodiimidazo[1,2-a:2',1'-c]pyrazine is equipped with a reflux condenser fitted with nitrogen inlet tube, a 500-mL pressure-equalizing addition funnel, and a...
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1,4,7,10-Tetraazacyclodedecane butyltriols of general formula IA in which R1 means hydrogen or a metal ion equivalent independent of one another and R2 means a butyltriol radical as well as their salts with organic or inorganic bases or amino acids are valuable pharmaceutical agents.
1,4,7,10-tetraazacyclododecane-1,4-diacetic acid of formula (I): as well as its chelated complex salts with bi-valent metal ions having atomic numbers from 20 to 31, 39, 42, 43, 44, 49, or from 57 to 83, as well as their salts with anions of physiologically acceptable organic acid selected from acetate...
1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs US 4885363 A. Abstract.
60239-18-1 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid. *Heterocyclic Compounds, 1-Ring Pharma Action Chelating Agents. Int J Rad Appl Instrum (B):469.
It has 8 coordination sites with metal ions (from 3 nitrogens and 5 oxygens). DOTA (1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid).
ACD/KOC (pH 7.4): Polar Surface Area: Polarizability