Refractory status epilepticus most commonly complicates an acute brain injury (stroke, trauma, infection, etc.) or a serious medical illness. It may also occur in people with a chronic seizure disorder. In a significant minority of cases, however, refractory SE strikes out of the blue and no cause can be...
Super-refractory status epilepticus is defined as status epilepticus that continues or recurs 24 h or more after the onset of anaesthetic therapy
Conclusions: Autoimmune encephalitis is the most commonly identified cause of new-onset refractory status epilepticus, but half remain cryptogenic. Outcome at discharge is poor but im-proves during follow-up.
Refractory status epilepticus occurs in 10-70% of adults [4-6] and children [7-9] with status epilepticus. Studies in.
Status epilepticus: causes, clinical features and consequences in 98 patients. Am J Med 1980; 69: 657-666. 23. Drislane FW, Lopez MR, Blum AS et al. Detection and treatment of re-. 190 Epileptologie 2012; 29. Refractory Status Epilepticus | R.Sutter and S. Rüegg.
This article reviews the approach to refractory status epilepticus and super-refractory status epilepticus, including management as well as common pathophysiological causes of these entities.
New-onset refractory status epilepticus (NORSE) is defined as refractory status epilepticus without an obvious cause after initial investigations; “initial” typically refers to 1-2 days, which is adequate time to rule out strokes, brain masses, drug overdoses, and herpes encephalitis.
Status epilepticus (SE) is an epileptic seizure of greater than five minutes or more than one seizure within a five-minute period without the person returning to normal between them. Previous definitions used a 30-minute time limit.
In persons with status epilepticus, if administration of a benzodiazepine and at least one antiepileptic drug has failed then management protocols for refractory status epilepticus should be put into effect. The article summarises the causes, effects...
While status epilepticus has been defined as more than 20-30 minutes of continuous seizure activity,1 this more correctly defines refractory status epilepticus as it usually reflects failure of treatment.2. AETIOLOGY Seizures may be caused by any of the disorders listed.