Most children with an episode of SE should be admitted for inpatient observation, evaluation, and treatment. Any child with persistent altered mental status (despite cessation of seizure activity) or with prolonged status epilepticus should be admitted to a pediatric critical care unit.
!!!!! 3. Both treatment and diagnostic evaluation should be started simultaneously. ! LPCH Pediatric Status Epilepticus Pathway. Immediate Management (0-5 minutes): • Non-invasive airway protection with optimal head/jaw positioning for airway patency.
,† Status epilepticus (SE) is a common pediatric neurologic emergency that refers to a prolonged seizure or recurrent seizures without a return to baseline mental status between seizures. Appropriate treatment strategies are necessary to prevent prolonged SE and its associated morbidity and mortality.
Pediatric Seizure and SE ED Therapy. Recommendations regarding the treatment of SE, published by the Working Group on Status Epilepticus, provide the basis for optimal SE management in the Emergency Department.
Here, we review the treatment options for pediatric refractory status epilepticus, provide an example of a protocol based on our experience and the limited available data, and highlight key issues that future investigations must confront.
Propofol has been used extensively in adult status epilepticus. However, the risk of propofol infusion syndrome is high in children and hence propofol is not approved for the treatment of pediatric status epilepticus in many countries .
Article history: Received 7 January 2012 Accepted 20 March 2012. abstract. We investigated the etiology, treatment, and prognosis of patients treated for status epilepticus at a pediatric intensive care unit.
Here we describe the use of allopregnanolone in two pediatric patients with super-refractory status epilepticus. This treatment allowed the general anesthetic infusions to be weaned with resolution of status epilepticus.
demonstrated in the treatment of status epilepticus resis-tant to diazepam, where valproate was found to be more effective than intravenous phenytoin in the pediatric popu-lation, with a better tolerability profile.
When nonconvulsive status epilepticus occurs or is suspected, emergency medical treatment in a hospital setting is needed.