,† Status epilepticus (SE) is a common pediatric neurologic emergency that refers to a prolonged seizure or recurrent seizures without a return to baseline mental status between seizures. Appropriate treatment strategies are necessary to prevent prolonged SE and its associated morbidity and mortality.
!!!!! 3. Both treatment and diagnostic evaluation should be started simultaneously. ! LPCH Pediatric Status Epilepticus Pathway. Immediate Management (0-5 minutes): • Non-invasive airway protection with optimal head/jaw positioning for airway patency.
Here, we review the treatment options for pediatric refractory status epilepticus, provide an example of a protocol based on our experience and the limited available data, and highlight key issues that future investigations must confront.
Treatment of Pediatric Status Epilepticus. Tobias Loddenkemper, MD.
Propofol has been used extensively in adult status epilepticus. However, the risk of propofol infusion syndrome is high in children and hence propofol is not approved for the treatment of pediatric status epilepticus in many countries .
Here we describe the use of allopregnanolone in 2 pediatric patients with super-refractory status epilepticus. This treatment allowed the general anesthetic infusions to be weaned with resolu-tion of status epilepticus. This is the first report of allo-pregnanolone use to treat status epilepticus in...
Treatment of Pediatric Status Epilepticus. Tobias LoddenkemperAffiliated withHarvard Medical School, Division of Epilepsy and Clinical Neurophysiology, Fegan 9, Children’s Hospital Boston Email author.
Pediatric Seizure and SE ED Therapy. Recommendations regarding the treatment of SE, published by the Working Group on Status Epilepticus, provide the basis for optimal SE management in the Emergency Department.
In cases of refractory status epilepticus, fur-ther treatment will depend on the setting. When pediatric intensive care is not available, phenobarbital or paraldehyde might be used.
Pediatric Status Epilepticus. Author: Rajesh Ramachandrannair, MBBS, MD, FRCPC. Chief Editor: Timothy E Corden, MD.