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Gq protein (Gαq, or Gq/11) is a heterotrimeric G protein subunit that activates phospholipase C (PLC). PLC in turn hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to diacyl glycerol (DAG) and inositol trisphosphate (IP3) signal transduction pathway.
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